《Mapu a Global Diabetes》
Pafupifupi 10 peresenti ya akuluakulu ali ndi matenda a shuga, ndipo theka la iwo samadziwa.
Mmodzi mwa anthu 13 ali ndi kulolerana kwa glucose molakwika
Mmodzi mwa ana asanu ndi mmodzi aliwonse amakhudzidwa ndi hyperglycemia pa nthawi ya mimba
Munthu m'modzi amamwalira masekondi 8 aliwonse ndi matenda a shuga ndi zovuta zake ...
--------International Diabetes Federatio
Kuchuluka kwa matenda a shuga komanso kufa kwambiri
Novembala 14 ndi Tsiku la Diabetes Padziko Lonse.Pafupifupi anthu 463 miliyoni azaka zapakati pa 20 ndi 79 amakhala ndi matenda ashuga padziko lonse lapansi, ambiri mwa iwo omwe ali ndi matenda amtundu wa 2.Izi zikufanana ndi mmodzi mwa akuluakulu 11, malinga ndi IDF's Diabetes Atlas yaposachedwa, kusindikiza kwachisanu ndi chinayi ku International Diabetes Federation.
Chochititsa mantha kwambiri ndi chakuti 50.1 peresenti ya akuluakulu padziko lonse omwe ali ndi matenda a shuga sadziwa kuti ali nawo.Chifukwa chosowa chithandizo chamankhwala, mayiko omwe ali ndi ndalama zochepa amakhala ndi chiwerengero chachikulu cha odwala omwe sanadziwike, pa 66.8 peresenti, pamene mayiko omwe ali ndi ndalama zambiri ali ndi 38.3 peresenti ya odwala omwe sanawazindikire.
32% ya anthu odwala matenda ashuga padziko lonse lapansi amadwala matenda amtima.Kuposa 80% ya matenda a impso otsiriza amayamba chifukwa cha matenda a shuga kapena matenda oopsa kapena zonsezi.Matenda a shuga a phazi ndi m'munsi amakhudza anthu 40 mpaka 60 miliyoni omwe ali ndi matenda a shuga.Pafupifupi 11.3% yaimfa padziko lonse lapansi imalumikizidwa ndi matenda ashuga.Pafupifupi 46.2% ya anthu omwe amafa ndi matenda a shuga anali pakati pa anthu ochepera zaka 60.
Type 2 shuga mellitus ndi kuchuluka kwa thupi lambiri kumawonjezera chiopsezo cha khansa yodziwika bwino: chiwindi, kapamba, endometrial, colorectal ndi khansa ya m'mawere.Pakali pano, mankhwala ochiritsira matenda a shuga nthawi zambiri amakhala payekha payekha mankhwala, masewera olimbitsa thupi ndi zakudya zoyenera, ndipo palibe mankhwala.
Chamba chachipatala chili ndi 'chandanda' cha matenda a shuga
Kafukufuku watsopano wofalitsidwa mu Journal JAMA Internal Medicine akuwonetsa kuti mankhwala opangidwa ndi chamba amathandiza kuchepetsa zizindikiro za mbewa za matenda a shuga.Pakuyesaku, kuchuluka kwa mbewa za matenda a shuga omwe amagwiritsa ntchito chamba kudatsika kuchokera pa 86% mpaka 30%, ndipo kutupa kwa kapamba kunaletsedwa ndikuchedwa, ndikuchepetsa ululu wamtsempha.Poyesera, gululo lidapeza zotsatira zabwino za chamba chachipatala pa matenda a shuga:
01
# Sinthani metabolism #
Kuchedwetsa kagayidwe kachakudya kumatanthauza kuti thupi silingathe kupanga mphamvu moyenera, limasokoneza magwiridwe antchito, kuphatikiza kasamalidwe ka shuga m'magazi, ndikupangitsa kunenepa kwambiri.Mafuta ochulukirapo m'thupi amachepetsa chidwi cha maselo am'magazi ku insulin, zomwe zimasokoneza mphamvu yawo yoyamwa shuga, yomwe imadziwikanso kuti insulin kukana.Kafukufuku wawonetsa kuti odwala omwe amagwiritsa ntchito chamba chachipatala amakhala ndi insulin yocheperako kukana komanso metabolism yachangu, yomwe imathandizira "kuwotcha mafuta" ndikuthandizira ma cell amafuta oyera kukhala ma cell a bulauni.
zimapukusidwa ndi ntchito monga mphamvu pa ntchito thupi motero kulimbikitsa tsiku lonse
kayendedwe ndi kagayidwe ka maselo m'thupi.
02
# Kuchepetsa kukana kwa insulini #
Maselo a m'magazi akayamba kukana insulini, amalephera kulimbikitsa kusuntha kwa glucose kupita ku maselo a cell, zomwe zimapangitsa kuti glucose achuluke.Chamba chachipatala chimatha kupititsa patsogolo mphamvu ya thupi kuyamwa ndikugwiritsa ntchito insulin moyenera.Kafukufuku wa 2013 wofalitsidwa mu American Journal of Medicine adasanthula akuluakulu 4,657, amuna ndi akazi, ndipo adapeza kuti odwala omwe amamwa chamba nthawi zonse amatsika ndi 16 peresenti pakusala kudya kwa insulin komanso kuchepa kwa 16 peresenti kwa insulin kukana.
03
# Kuchepetsa kutupa kwa kapamba #
Kutupa kosatha kwa ma cell a kapamba ndi chizindikiro choyambirira cha matenda a shuga 1, ziwalo zikapsa, zimatha kutulutsa insulin.Chamba chachipatala chimathandiza kuchepetsa kutupa, kuchepetsa kutupa, komanso kuwonjezera nthawi zonse kungathandize kuchepetsa kutupa kwa kapamba ndikuthandizira kuchepetsa kuyambika kwa matendawa.
04
# Kupititsa patsogolo kayendedwe ka magazi #
Matenda oopsa kwambiri ndiye vuto lomwe limafala kwambiri pamtundu wa 1 komanso mtundu wa 2 shuga.Chamba chachipatala chimatha kufutukula mitsempha ya magazi, kulimbikitsa kutuluka kwa magazi, kuchepetsa kuthamanga kwa magazi, ndi kupewa kuthamanga kwa magazi.
Mu 2018, lipoti linatulutsidwa pa Convention on Biological Diversity, lomwe limafotokoza momveka bwino kuti CBD ndi chinthu chachilengedwe komanso chotetezeka ndipo palibe kuthekera kochitira nkhanza.Ngakhale pa Mlingo wokwera mpaka 1,500 mg patsiku, palibe zotsatira zoyipa.Ndiye, kodi chamba chachipatala ndichabwino kuchiza matenda a shuga?Kuyanjana kwamankhwala komwe kungachitike kuyenera kuganiziridwa apa.CBD imatha kukumana ndi kusinthasintha pang'ono kwapakamwa komanso kusinthasintha kwachilakolako polumikizana ndi mankhwala ena, koma izi sizichitika kawirikawiri.
Kodi mlingo woyenera wa CBD wa matenda ashuga ndi uti?Bungwe la US Food and Drug Administration (FDA) silinayankhe bwino funsoli, chifukwa nyonga ya munthu aliyense, kulemera kwa thupi, zaka, jenda, ndi kagayidwe kake ndi zina mwazinthu zambiri zomwe zimakhudza.Chifukwa chake, malingaliro wamba ndikuti odwala omwe ali ndi matenda ashuga amayamba ndikugwiritsa ntchito kuwunika kwa mlingo wochepa komanso kusintha kwanthawi yake.Ogwiritsa ambiri sadzakhala upambana 25 milligrams tsiku kudya CBD, ndipo pansi pa zinthu zina, mulingo woyenera kwambiri mlingo wa 100 mg kwa 400 mg.
CB2 agonist -caryophyllene BCP ndi yothandiza mu mtundu 2 shuga
Ofufuza aku India posachedwapa adasindikiza pepala mu European Journal of Pharmacology kuwonetsa zotsatira za CB2 agonist -carbamene BCP pamtundu wa 2 shuga.Ofufuzawo adapeza kuti BCP imayambitsa mwachindunji cholandilira cha CB2 pama cell a beta omwe amapanga insulin mu kapamba, zomwe zimapangitsa kuti insulini itulutsidwe ndikuwongolera momwe kapamba amagwirira ntchito.Panthawi imodzimodziyo, kuyambitsa kwa BCP kwa CB2 kumakhudza kwambiri zovuta za matenda a shuga, monga nephropathy, retinopathy, cardiomyopathy ndi neuropathy. masamba obiriwira, masamba obiriwira.)
# CBD imachulukitsa kupanga insulin mwa kuyambitsa cholandilira ana amasiye GPR55 #
Ofufuza aku Brazil ochokera ku Yunivesite ya California, Marin, adaphunzira za thanzi la CBD mu mtundu wa nyama wa matenda a shuga a ischemia.Ofufuzawa adakopa matenda amtundu wa 2 mwa mbewa zamphongo ndipo adapeza kuti CBD idakhudza kwambiri matenda a shuga powonjezera insulin ya plasma.
CBD imatha kutsitsa shuga m'magazi mu mbewa zomwe zikuipiraipira chifukwa cha kusowa kwa okosijeni.Njira yogwirira ntchito imaganiziridwa kuti CBD ikhoza kuonjezera kupanga insulini mwa kuyambitsa cholandilira cha ana amasiye GPR55. kumasula.
Chamba chachipatala chitha kugwiritsidwa ntchito pochiza khansa, kupondereza khunyu, minyewa, kukokana, komanso kuchepetsa ululu.Izi zidzayendetsa kukula, pomwe msika wa chamba wamankhwala padziko lonse lapansi ukuyembekezeka kufika $148.35 biliyoni pofika 2026, malinga ndi zowona zaposachedwa.《Malipoti ndi Deta》.
Nthawi yotumiza: Dec-04-2020